Bioactive glasses in soft tissue repair
نویسندگان
چکیده
nerve regeneration. T main body of research involving bioactive glasses (BGs) has been devoted to applications in orthopedics and dentistry, given that the original composition 45S5 BioglassTM was developed to treat non-self-healing bone defects, such as bullet trauma or cancer. Because of their high bioactivity, BGs directly bond to bone. That bioactivity recently has been appreciated to extend to interaction with soft tissues as well. Many of the cellular processes involved in the early stages of soft tissue regeneration are affected by ionic dissolution products released by BGs, and an important aspect of BG applications in soft tissue repair strategies is their angiogenic potential. Fixation of shoulder prostheses (e.g., rotator cuff repair)
منابع مشابه
تهیه، مشخصهیابی و ارزیابی مقایسهای زیست فعالی سه نوع نانو پودر شیشه زیست فعال برای کاربردهای پزشکی
Fabrication of biomaterials with ability to form a bond with bone tissue for bone skeletal system repair is one of the biomaterial science aims. Bioactive glasses containing CaO-SiO2-P2O5 are among the most important groups used in biomedicine and dentistry such as bone defect repair and maxillo-facial reconstruction. The aim of this work was preparation and characterization of nano particle b...
متن کاملPotential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering
Repair and regeneration of disorders affecting cardiac and pulmonary tissues through tissue-engineering-based approaches is currently of particular interest. On this matter, different families of bioactive glasses (BGs) have recently been given much consideration with respect to treating refractory diseases of these tissues, such as myocardial infarction. The inherent properties of BGs, includi...
متن کاملCobalt-containing bioactive glasses reduce human mesenchymal stem cell chondrogenic differentiation despite HIF-1α stabilisation
Bioactive glasses (BGs) are excellent delivery systems for the sustained release of therapeutic ions and have been extensively studied in the context of bone tissue engineering. More recently, due to their osteogenic properties and expanding application to soft tissue repair, BGs have been proposed as promising materials for use at the osteochondral interface. Since hypoxia plays a critical rol...
متن کاملBioactive Glass Nanoparticles: From Synthesis to Materials Design for Biomedical Applications
Thanks to their high biocompatibility and bioactivity, bioactive glasses are very promising materials for soft and hard tissue repair and engineering. Because bioactivity and specific surface area intrinsically linked, the last decade has seen a focus on the development of highly porous and/or nano-sized materials. This review emphasizes the synthesis of bioactive glass nanoparticles and materi...
متن کاملBioactive Hierarchical Structures for Genetic Control of Bone Morphogenesis
For thirty years it has been known that certain compositions of Na 2 O-CaO-P 2 O 5 -SiO 2 glasses will form a mechanically strong, chemical bond to bone. These materials have become known as bioactive glasses and the process of bonding is called bioactive fixation. Bioactive glasses are widely used clinically in the repair of bone defects. Recent research at the Imperial College Tissue Engineer...
متن کامل